Although many modern skin fillers are marketed as non-permanent, the filled tissues can become calcified, and these tissues become hardened and lumpy.  It is sometimes possible to improve this with firm massage and injection with a combination steroid mixture, but some calcified filler masses have to be cut out of the tissues to resolve the uneven appearance of the skin.

Filler in the lips can become so hard as to erode through the delicate lip surface, causing ulcers and sores.

The best course of action to avoid this is to avoid artificial fillers.  If filling treatment is a priority, the best natural filler is your own fat, and this can be removed from a place where it is unwanted, and inserted where required.  Fat is less suitable as a filler in the lips, however, and a dermis graft, again taken from your own tissues, is usually best in this situation.

Fillers 1 July 25 045.jpg
Fillers 2 July 25 041.jpg